PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Clinical trials for PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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Could an old malaria drug help beat melanoma?
Disease control TerminatedThis study tested whether adding hydroxychloroquine (a drug used for malaria) to standard targeted therapy (dabrafenib and trametinib) could help control advanced melanoma that has a specific gene change (BRAF V600E/K) and high LDH levels. The trial was stopped early after enroll…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 03:17 UTC
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New drug combo shows promise for Hard-to-Treat cancers, but study ends early
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combo could shrink tumors or slo…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 03:09 UTC
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Engineered virus takes on deadly skin cancer in early trial
Disease control TerminatedThis early-phase trial tested a specially modified virus (VSV-IFNbetaTYRP1) in 12 people with advanced melanoma that had spread or could not be removed. The virus was injected directly into tumors and into a vein to see if it could safely trigger the immune system to attack cance…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Cancer brain metastasis drug combo trial halted early
Disease control TerminatedThis study tested two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the best dose and see if the combination could slow or stop tumor growth. The trial was stopped early after enrolling only 8 participants, so no clear…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Promising combo therapy for brain melanoma halted early
Symptom relief TerminatedThis early-stage trial tested whether adding a device that creates electric fields (NovoTTF-200M) to standard radiation and immunotherapy could safely treat melanoma that has spread to the brain. Only 1 person took part before the study was stopped. The main goal was to check for…
Matched conditions: PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: Symptom relief
Last updated May 17, 2026 03:10 UTC