PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Clinical trials for PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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Could an old malaria drug help beat melanoma?
Disease control TerminatedThis study tested whether adding hydroxychloroquine (a drug used for malaria) to standard targeted therapy (dabrafenib and trametinib) could help control advanced melanoma that has a specific gene change (BRAF V600E/K) and high LDH levels. The trial was stopped early after enroll…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 03:17 UTC
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Melanoma drug combo shows promise before surgery in early trial
Disease control TerminatedThis study tested two drugs, encorafenib and binimetinib, given before surgery to people with stage IIIB-D melanoma that had spread to lymph nodes. The goal was to see if the drugs could shrink or eliminate tumors before they were removed. Only 3 people enrolled before the study …
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 03:15 UTC
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New drug combo shows promise for Hard-to-Treat cancers, but study ends early
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combo could shrink tumors or slo…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 03:09 UTC
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Engineered virus takes on deadly skin cancer in early trial
Disease control TerminatedThis early-phase trial tested a specially modified virus (VSV-IFNbetaTYRP1) in 12 people with advanced melanoma that had spread or could not be removed. The virus was injected directly into tumors and into a vein to see if it could safely trigger the immune system to attack cance…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 15, 2026 11:57 UTC