PATHOLOGIC STAGE IIB GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA AJCC V8
Clinical trials for PATHOLOGIC STAGE IIB GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA AJCC V8 explained in plain language.
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New combo attack on stomach cancer before surgery
Disease control OngoingThis study is testing a new treatment approach for patients with stomach or gastroesophageal cancer that can be surgically removed. It combines two immunotherapy drugs (nivolumab and ipilimumab) with chemotherapy and radiation before surgery, aiming to shrink the tumor and help t…
Matched conditions: PATHOLOGIC STAGE IIB GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Double-Punch immunotherapy trial aims to wipe out tumors before esophageal cancer surgery
Disease control OngoingThis study is testing whether a powerful combination of treatments can shrink or eliminate tumors before surgery for esophageal and gastroesophageal junction cancers. Patients receive standard chemotherapy and radiation alongside an immunotherapy drug (pembrolizumab), followed by…
Matched conditions: PATHOLOGIC STAGE IIB GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Modified virus tested to attack tough esophageal cancers
Disease control OngoingThis early-stage study is testing the safety of adding a specially designed virus (OBP-301) to standard chemotherapy and radiation for patients with advanced esophageal or gastroesophageal cancer who are not candidates for surgery. The virus is meant to infect and kill cancer cel…
Matched conditions: PATHOLOGIC STAGE IIB GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New combo therapy aims to shrink tumors before esophageal cancer surgery
Disease control OngoingThis study is testing whether adding immunotherapy drugs to standard chemotherapy before surgery can better control cancer in the esophagus or where the stomach meets the esophagus. The goal is to shrink the tumor as much as possible before an operation to remove it. Researchers …
Matched conditions: PATHOLOGIC STAGE IIB GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC