OTOTOXICITY
Clinical trials for OTOTOXICITY explained in plain language.
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Can a pill save hearing during CF lung treatment?
Disease control CompletedThis study tests whether SPI-1005, a drug containing ebselen, can prevent hearing loss in people with cystic fibrosis who are receiving IV tobramycin for a lung infection. About 40 participants will receive either a placebo or one of three doses of SPI-1005 for 21 days. Researche…
Matched conditions: OTOTOXICITY
Phase: PHASE2 • Sponsor: Sound Pharmaceuticals, Incorporated • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Could a common cholesterol drug protect cancer Patients' hearing?
Symptom relief CompletedThis study looked at whether taking statins (cholesterol-lowering drugs) can reduce hearing loss caused by platinum-based chemotherapy in people with solid tumors. 56 adults who were about to start chemotherapy took part. The goal was to see if statins could protect their ears fr…
Matched conditions: OTOTOXICITY
Phase: PHASE1, PHASE2 • Sponsor: Minia University • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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COVID drugs and vaccines: silent threat to hearing?
Knowledge-focused CompletedThis completed study looked at whether medications used for COVID-19 or the COVID-19 vaccine can harm hearing. Researchers compared hearing test results among 90 adults aged 18-35: those who had COVID-19 and took medications, those who had COVID-19 but took no medications, and a …
Matched conditions: OTOTOXICITY
Sponsor: Zonguldak Bulent Ecevit University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC