OROFACIAL PAIN
Clinical trials for OROFACIAL PAIN explained in plain language.
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New personalized therapy aims to ease chronic jaw pain
Symptom relief OngoingThis study compares two behavioral treatments for temporomandibular joint disorders (TMD), a common cause of jaw and face pain. 160 adults with long-term jaw pain will receive either standard dental care plus a highly individualized coping skills program, or standard care plus co…
Matched conditions: OROFACIAL PAIN
Phase: NA • Sponsor: UConn Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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New online program aims to ease chronic facial pain without drugs
Symptom relief OngoingThis study tests a self-guided web program called Face-Forward-Web for adults with chronic orofacial pain (lasting over 3 months). The program includes five 30-minute video sessions teaching relaxation, mindfulness, and coping skills. Researchers will enroll up to 30 participants…
Matched conditions: OROFACIAL PAIN
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Could CBD and CBN ease your jaw pain and headaches?
Symptom relief ENROLLING_BY_INVITATIONThis study is testing whether a drink containing CBD and CBN can reduce facial pain and headaches caused by muscle tension. 42 adults with pain lasting over 3 months will be randomly assigned to receive either the CBD/CBN drink or a placebo. Researchers will measure pain and musc…
Matched conditions: OROFACIAL PAIN
Phase: PHASE2, PHASE3 • Sponsor: Wroclaw Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Zapping the brain to stop face pain: new hope for sufferers
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether non-invasive brain stimulation (tDCS or TMS) can reduce chronic orofacial pain—pain in the face, mouth, or jaw that lasts more than 3 months. About 50 adults who haven't gotten enough relief from standard treatments will receive either real stimulation or…
Matched conditions: OROFACIAL PAIN
Phase: NA • Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Could your blood predict jaw pain? new study investigates cannabinoid receptors
Knowledge-focused ENROLLING_BY_INVITATIONThis study explores whether the levels of certain receptors (CB1, CB2, TRPV-1) in the blood are linked to chronic orofacial pain from jaw muscles. Researchers will compare 102 adults with and without this pain, using blood tests and clinical exams. The goal is to understand how t…
Matched conditions: OROFACIAL PAIN
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC