NONALCOHOLIC STEATOHEPATITIS

This study tests an experimental drug, GSK4532990, in 284 adults with nonalcoholic steatohepatitis (NASH) and advanced liver scarring. The goal is to see if the drug can improve liver fibrosis and inflammation compared to a placebo over 52 weeks. Participants must have a liver bi…

This study looks at whether eating three soybean-oil-based foods each day for 16 weeks can lower fat buildup in the liver and belly fat in people with nonalcoholic fatty liver disease. Participants keep their usual weight during the trial. The goal is to see if changing the type …

This study tests an experimental drug called efinopegdutide in 80 adults with liver scarring (cirrhosis) caused by metabolic dysfunction-associated steatohepatitis (MASH), a type of fatty liver disease. The goal is to see if the drug can reduce liver fat, inflammation, and scarri…

This phase II trial tests whether lisinopril, a widely used blood pressure medication, can prevent liver damage from getting worse in people with non-alcoholic fatty liver disease (NAFLD). The study enrolls 45 adults with advanced liver scarring and measures changes in fibrosis m…

This study looks at how often people with type 1 diabetes have fatty liver disease and serious liver scarring. Researchers used a special ultrasound and blood tests to check 533 adults. The goal is to find high-risk patients who need a liver specialist.

This study aims to understand how bariatric surgery affects the body's tissues, like fat, muscle, and liver, and how it improves insulin sensitivity. Researchers will collect tissue and blood samples from 500 adults undergoing surgery or other procedures. The goal is to learn the…