NEURO-DEGENERATIVE DISEASE

This study tests a drug called cobimetinib in children and adults with Langerhans cell histiocytosis and similar disorders that have not responded to standard treatments. Cobimetinib blocks a faulty growth signal in cells, aiming to shrink tumors and slow disease progression. The…

This study tests whether custom, 3D-printed cutlery handles can help elderly patients with neurodegenerative diseases eat more independently. Researchers will give 75 patients in rehabilitation care handles sized to their grip and measure changes in eating ability and food intake…

This study uses special eye cameras to take detailed pictures of the back of the eye in 2000 adults with and without brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. The goal is to find changes in the eye that might signal early signs of these conditions. No …

This study follows 20 people with a rare nerve disease called CMT4J for up to 2 years. Researchers will track symptoms and health changes to better understand how the disease progresses. The goal is to find better ways to measure the disease, which could help design future treatm…

This study is enrolling 1 million adults aged 18 and older to track their health over many years, possibly for life. Researchers will collect health measurements and follow participants to see who develops diseases or dies, and why. The goal is to create better ways to predict ag…

This study looks at how stroke changes brain activity when people walk while doing another task, like listening or navigating. Researchers will measure brain signals and walking patterns in 50 adults who had a stroke at least 6 months ago. The goal is to better understand these c…

This study looks at the experiences of extended family members—like grandchildren, siblings, and nieces/nephews—who care for a loved one with dementia. Researchers want to learn what challenges these caregivers face, what services they use, and what barriers prevent them from get…