NEOPLASMS, COLORECTAL
Clinical trials for NEOPLASMS, COLORECTAL explained in plain language.
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New drug targets tough cancers in Mid-Stage trial
Disease control OngoingThis study tests an experimental drug called 9-ING-41, which blocks a protein (GSK-3β) that helps cancers grow. It is given alone or with chemotherapy to 350 adults with advanced or hard-to-treat cancers like pancreatic, breast, lung, or bone cancer. The goal is to see if the dru…
Matched conditions: NEOPLASMS, COLORECTAL
Phase: PHASE2 • Sponsor: Actuate Therapeutics Inc. • Aim: Disease control
Last updated May 17, 2026 11:32 UTC
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New pill targets genetic weak spot in aggressive tumors
Disease control OngoingThis study tests an experimental oral drug (GSK4418959) in adults with advanced solid tumors that have specific genetic features (dMMR or MSI-H). The drug aims to shrink tumors by blocking a DNA repair protein. The trial will check safety, side effects, and how well the drug work…
Matched conditions: NEOPLASMS, COLORECTAL
Phase: PHASE1, PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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New drug combo targets hard-to-treat cancers with KRAS mutation
Disease control OngoingThis study tests a new drug called JDQ443, given alone or with other treatments, for people with advanced solid tumors that have a specific change in the KRAS gene (G12C). The goal is to find safe doses and see if the drug can shrink tumors. About 74 adults with lung or colorecta…
Matched conditions: NEOPLASMS, COLORECTAL
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 06, 2026 16:03 UTC