NAFLD
Clinical trials for NAFLD explained in plain language.
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Exercise as medicine: new study tests best dose for fatty liver disease
Disease control Recruiting nowThis study looks at how much exercise works best to lower liver fat in people with nonalcoholic steatohepatitis (NASH), a serious liver condition. Researchers will enroll 45 sedentary adults aged 18-69 with NASH and early-stage liver scarring. Participants will follow different e…
Matched conditions: NAFLD
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 17, 2026 02:23 UTC
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Could a common heart pill treat fatty liver?
Disease control Recruiting nowThis study tests whether a low dose of digoxin, a drug normally used for heart problems, can help people with a severe type of fatty liver disease called NASH (also known as MASH). About 144 adults with confirmed NASH and liver scarring will take digoxin or a placebo for a period…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated May 17, 2026 02:23 UTC
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New study aims to spare NAFLD patients from unnecessary liver biopsies
Diagnosis Recruiting nowThis study compares two step-by-step strategies to diagnose advanced liver fibrosis in people with NAFLD (fatty liver disease). Both strategies start with a simple blood test, then use a more advanced test only if needed, to avoid invasive liver biopsies. About 1,045 participants…
Matched conditions: NAFLD
Phase: NA • Sponsor: University Hospital, Angers • Aim: Diagnosis
Last updated May 17, 2026 02:23 UTC
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Mini livers in a dish reveal how a common gene variant fuels fatty liver disease
Knowledge-focused Recruiting nowThis study uses tiny, lab-grown liver models called organoids to understand how a specific gene change (PNPLA3 I148M) contributes to non-alcoholic steatohepatitis (NASH), a serious form of fatty liver disease. Researchers will create these models from liver cells donated by 60 ad…
Matched conditions: NAFLD
Phase: NA • Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated May 17, 2026 02:26 UTC
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Tiny beginnings, big liver risk: diet study seeks answers
Knowledge-focused Recruiting nowThis study looks at why people born with low birth weight are more likely to develop fatty liver disease (NAFLD). Researchers will put 8 adults with NAFLD on a 4-week low-calorie diet to see if it reduces liver fat. The goal is to understand how the body stores fat and whether th…
Matched conditions: NAFLD
Phase: NA • Sponsor: Steno Diabetes Center Copenhagen • Aim: Knowledge-focused
Last updated May 17, 2026 02:17 UTC
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Hormone link to fatty liver in young women under microscope
Knowledge-focused Recruiting nowThis study looks at how androgens (a type of sex hormone) might affect fatty liver disease in young women. Researchers will compare women with PCOS (who often have high androgen levels) to those without PCOS. The goal is to understand changes in liver fat and stiffness over time.…
Matched conditions: NAFLD
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC