MYELODYSPLASIA
Clinical trials for MYELODYSPLASIA explained in plain language.
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Can a pill keep blood cancer at bay after a stem cell transplant?
Disease control CompletedThis phase III trial is testing whether taking oral azacitidine as a maintenance therapy after an allogeneic stem cell transplant can help prevent relapse in people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Participants are randomly assigned to receive…
Matched conditions: MYELODYSPLASIA
Phase: PHASE3 • Sponsor: University of Birmingham • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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New stem cell transplant approach shows promise for blood cancer patients without full matches
Disease control CompletedThis Phase 3 trial tested a stem cell transplant using blood stem cells from a half-matched (haploidentical) donor in 21 people with various blood cancers. The goal was to see if this approach could help patients who don't have a fully matched donor. Participants received chemoth…
Matched conditions: MYELODYSPLASIA
Phase: PHASE3 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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One cord blood unit may replace two in stem cell transplants for blood cancer
Disease control CompletedThis study tested a new way to treat blood cancers like leukemia in 16 adults who did not have a standard bone marrow donor. Doctors used a single unit of cord blood that was grown in a lab to increase the number of stem cells before transplant. The goal was to see if this method…
Matched conditions: MYELODYSPLASIA
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New drug cocktail aims to tame deadly transplant complication
Disease control CompletedThis study tested whether adding pacritinib to standard immune-suppressing drugs (sirolimus and tacrolimus) could prevent graft-versus-host disease (GVHD) in 40 patients receiving stem cell transplants for blood cancers. GVHD occurs when donor immune cells attack the recipient's …
Matched conditions: MYELODYSPLASIA
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Cord blood boost: new technique shows promise for tough leukemia cases
Disease control CompletedThis study tested a new way to prepare cord blood for transplant in 30 people with high-risk leukemia or myelodysplasia. The cord blood was treated with a molecule called UM171 to help it grow more stem cells. The goal was to see if this approach is safe and helps patients recove…
Matched conditions: MYELODYSPLASIA
Phase: PHASE2 • Sponsor: ExCellThera inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Heart iron levels measured in Transfusion-Dependent patients
Knowledge-focused CompletedThis study measured how often iron builds up in the heart muscle of people who receive many blood transfusions. Researchers used MRI scans to check heart iron levels in 110 patients with thalassemia, sickle cell disease, or myelodysplasia. The goal was to understand how common th…
Matched conditions: MYELODYSPLASIA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC