MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Clinical trials for MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE explained in plain language.
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New hope for progressive MS: drug aims to slow disability
Disease control OngoingThis study tests whether ocrelizumab (Ocrevus) can slow disability worsening in adults with primary progressive multiple sclerosis (PPMS), including those with more advanced disease. About 1,000 participants receive either the drug or a placebo, and researchers measure changes in…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New daily pill takes on standard MS infusion in major disability battle
Disease control OngoingThis study compares a new daily oral medication, fenebrutinib, with the standard infusion ocrelizumab in 985 adults with primary progressive multiple sclerosis (PPMS). The goal is to see which treatment better delays worsening disability. Participants receive either fenebrutinib …
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Can a common supplement slow MS brain damage? new trial seeks answers.
Disease control OngoingThis study tests whether N-acetyl cysteine (NAC), a supplement, can protect the brain in people with progressive multiple sclerosis (MS). About 98 adults with primary or secondary progressive MS will receive either NAC or a placebo for 15 months. Researchers will measure brain sh…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: PHASE2 • Sponsor: Emmanuelle Waubant, MD PhD • Aim: Disease control
Last updated May 05, 2026 11:56 UTC
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Brain study seeks clues to cognitive decline in progressive MS
Knowledge-focused OngoingThis study follows 66 people with primary progressive multiple sclerosis (PPMS) and healthy volunteers over 2 years to see how thinking skills like memory and attention change. Researchers use brain scans and thinking tests to link brain changes with cognitive decline. The goal i…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC