MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Clinical trials for MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE explained in plain language.
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New daily pill could rival infusion for slowing progressive MS
Disease control OngoingThis phase 3 trial compares two drugs for primary progressive multiple sclerosis (PPMS), a form of MS that steadily worsens. About 985 adults with PPMS will receive either daily oral fenebrutinib or intravenous ocrelizumab (plus matching placebos) to see which better delays disab…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can a common supplement slow MS brain damage? new trial seeks answers.
Disease control OngoingThis study tests whether N-acetyl cysteine (NAC), a supplement, can protect the brain in people with progressive multiple sclerosis (MS). About 98 adults with primary or secondary progressive MS will receive either NAC or a placebo for 15 months. Researchers will measure brain sh…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: PHASE2 • Sponsor: Emmanuelle Waubant, MD PhD • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New hope for progressive MS: ocrelizumab trial targets disability
Disease control OngoingThis phase 3 trial tests whether ocrelizumab (Ocrevus) can slow disability progression in adults with primary progressive multiple sclerosis (PPMS). Over 1,000 participants receive either the drug or a placebo. The main goal is to see if the drug delays worsening of hand function…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New study tracks brain decline in progressive MS
Knowledge-focused OngoingThis study follows 66 people with primary progressive multiple sclerosis (PPMS) and healthy volunteers for two years to understand how thinking and memory change over time. Participants take cognitive tests and undergo MRI scans to see how brain tissue damage relates to mental de…
Matched conditions: MULTIPLE SCLEROSIS, PRIMARY PROGRESSIVE
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC