MOTOR NEURON DISEASE
Clinical trials for MOTOR NEURON DISEASE explained in plain language.
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Can a common alcoholism drug help slow ALS? new trial begins
Disease control OngoingThis early-stage study tests the safety of acamprosate, a drug used for alcohol dependence, in 30 adults with ALS who have a specific mutation in the C9orf72 gene. Participants take the pill three times daily for 24 weeks and undergo regular checkups, breathing tests, and spinal …
Matched conditions: MOTOR NEURON DISEASE
Phase: PHASE1 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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ALS drug trial pulled before it even started
Disease control TerminatedThis was a planned phase 2 trial to test IC14, a monoclonal antibody, in 50 people with rapidly progressing ALS. Participants would have received intravenous IC14 or placebo twice weekly for 12 weeks. The study was withdrawn before any patients were enrolled, so no data on safety…
Matched conditions: MOTOR NEURON DISEASE
Phase: PHASE2 • Sponsor: Implicit Bioscience • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Massive genetic study aims to unlock secrets of rare metabolic diseases
Knowledge-focused ENROLLING_BY_INVITATIONThis study will collect and analyze genetic data from 1000 people with suspected inherited metabolic diseases, including conditions like epilepsy and mitochondrial disorders. Researchers at Karolinska University Hospital aim to improve diagnosis by using advanced genetic testing …
Matched conditions: MOTOR NEURON DISEASE
Sponsor: Region Stockholm • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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New MRI scans could unlock ALS mysteries and speed up drug discovery
Knowledge-focused OngoingThis study tests whether advanced MRI techniques can measure brain changes in people with ALS (Lou Gehrig's disease). Researchers will scan 119 participants three times over 8 months to see if these scans can track the disease and help diagnose it earlier. The goal is to create b…
Matched conditions: MOTOR NEURON DISEASE
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New headset lets ALS patients type with their brain
Knowledge-focused OngoingThis study is testing a new, comfortable headset that reads brain signals to help people with ALS type on a virtual keyboard. The goal is to improve the device so it can be used in daily life. Five people with ALS will try the headset, and researchers will measure how easy it is …
Matched conditions: MOTOR NEURON DISEASE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC