MOOD DISORDER
Clinical trials for MOOD DISORDER explained in plain language.
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New therapy aims to help teens battling addiction and anxiety
Disease control CompletedThis study tests a new behavioral therapy called OPT-A for teenagers who have both substance use problems and mood or anxiety disorders. 140 teens aged 10-17 will receive either OPT-A or standard treatment. Researchers will track substance use and mental health for 18 months to s…
Matched conditions: MOOD DISORDER
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Nurse Check-Ins after suicide attempt show promise in preventing repeat crisis
Prevention CompletedThis study tested whether personalized, intensive nursing follow-up (by phone, home visits, or hospital consultations) after a suicide attempt could prevent another attempt or crisis in people with mood disorders. 380 participants were followed for one year. The goal was to see i…
Matched conditions: MOOD DISORDER
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Prevention
Last updated Jun 27, 2026 13:01 UTC
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Could a headset prevent suicide? small study tests home brain stimulation
Prevention CompletedThis study tested whether a home-based brain stimulation device (tDCS) could help prevent suicidal thoughts in adults recently discharged from the hospital for mood disorders. Thirty-three participants used the headset for 30 minutes a day over two weeks, supervised remotely. The…
Matched conditions: MOOD DISORDER
Phase: NA • Sponsor: University of Rochester • Aim: Prevention
Last updated Jun 27, 2026 09:02 UTC
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Online group therapy helps workers with depression get back on the job
Symptom relief CompletedThis study tested an online group program called Healthy Minds for people on sick leave due to depression, anxiety, or adjustment disorders. 123 participants either joined the 8-week program or received standard care. Researchers tracked their return to work, symptoms, and job fu…
Matched conditions: MOOD DISORDER
Phase: NA • Sponsor: Université du Québec a Montréal • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Online mental health program shows promise for depression
Symptom relief CompletedThis study tested a digital mental health program for adults with depressive symptoms. The program includes nine online modules covering topics like positive thinking, relaxation, and healthy habits. Researchers compared results between people with diagnosed mood disorders and th…
Matched conditions: MOOD DISORDER
Phase: NA • Sponsor: Chang Hsiu-Ju • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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France pilots collaborative mental health model in primary care
Knowledge-focused CompletedThis completed study looked at how well a collaborative care model works for common mental health issues like anxiety and depression in four French health clinics. The model involves a care manager who coordinates between family doctors and mental health specialists. Researchers …
Matched conditions: MOOD DISORDER
Phase: NA • Sponsor: Dr Nadia YOUNES • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Hormones and mood: a deep dive into perimenopause
Knowledge-focused CompletedThis study looked at how hormone changes during perimenopause (the time around menopause) might affect mood and behavior. Over 1,100 women participated, including those with depression symptoms and healthy volunteers. No treatments were given; instead, researchers used surveys an…
Matched conditions: MOOD DISORDER
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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MRI reveals brain differences in violent suicide attempts
Knowledge-focused CompletedThis study used MRI brain scans and computer tasks to understand how people who attempted suicide make decisions. Researchers compared three groups: those who used violent means, those who used non-violent means, and healthy volunteers. The goal was to find brain activity pattern…
Matched conditions: MOOD DISORDER
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Inside the mind: what really happens during PMS?
Knowledge-focused CompletedThis completed study from the National Institute of Mental Health looked at over 1,500 women to better understand the symptoms of premenstrual syndrome (PMS) and a severe form called PMDD. Researchers used interviews, rating scales, and hormone tests to track mood and behavior ch…
Matched conditions: MOOD DISORDER
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Pandemic stress under the microscope: 3,655 adults share their mental health struggles
Knowledge-focused CompletedThis completed study from the National Institute of Mental Health surveyed over 3,600 English-speaking adults online every two weeks for six months. Researchers asked about mental health symptoms, stress, and behaviors during the COVID-19 pandemic. The goal was to understand how …
Matched conditions: MOOD DISORDER
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC