MITRAL VALVE REGURGITATION
Clinical trials for MITRAL VALVE REGURGITATION explained in plain language.
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New catheter device offers hope for leaky heart valve patients
Disease control CompletedThis study tested a new device called the Edwards PASCAL system, which repairs leaky mitral heart valves using a thin tube inserted through a blood vessel, avoiding open-heart surgery. It involved 124 adults with moderate-to-severe mitral regurgitation who were candidates for sur…
Matched conditions: MITRAL VALVE REGURGITATION
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Heart valve clip shows promise for heart failure patients in Real-World study
Disease control CompletedThis study tested a device called MitraClip in 162 heart failure patients with a leaky mitral valve (mitral regurgitation). The device is clipped onto the valve to reduce leakage. The goal was to see if it is safe and effective in real-world conditions. All patients had severe sy…
Matched conditions: MITRAL VALVE REGURGITATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New heart valve fix without open surgery shows promise in High-Risk patients
Disease control CompletedThis study tested a new device called the Tiara valve, which is implanted through a small tube in the chest to replace the leaky mitral valve without open-heart surgery. It enrolled 157 people with severe mitral regurgitation who were considered too high-risk for traditional surg…
Matched conditions: MITRAL VALVE REGURGITATION
Phase: NA • Sponsor: Shockwave Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Nerve block eases pain after heart valve repair, cuts opioid use
Symptom relief CompletedThis study tested whether a nerve block (serratus anterior plane block) can reduce pain and the need for strong painkillers after minimally invasive mitral valve repair. 78 adults having this heart surgery were randomly assigned to receive either the nerve block or a placebo. The…
Matched conditions: MITRAL VALVE REGURGITATION
Phase: NA • Sponsor: Universitätsklinikum Hamburg-Eppendorf • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC