MELANOMA STAGE III
Clinical trials for MELANOMA STAGE III explained in plain language.
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New vaccine combo shows promise in advanced skin cancer trial
Disease control OngoingThis study tests two experimental cancer vaccines, SCIB1 and iSCIB1+, when added to standard immunotherapy drugs (nivolumab with ipilimumab or pembrolizumab) for people with advanced melanoma that cannot be removed by surgery. The goal is to see if the vaccines are safe and can i…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Scancell Ltd • Aim: Disease control
Last updated May 17, 2026 03:09 UTC
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New biosimilar aims to match keytruda in melanoma fight
Disease control OngoingThis study compares FYB206, a biosimilar (a very similar copy) of the cancer drug Keytruda, to the original Keytruda in 96 adults with stage IIB/IIC or III melanoma that has been completely removed by surgery. The goal is to see if FYB206 stays in the body the same way as Keytrud…
Matched conditions: MELANOMA STAGE III
Phase: PHASE1 • Sponsor: Formycon AG • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Immunotherapy combo shows promise in stopping melanoma recurrence after surgery
Disease control OngoingThis study tests whether giving immunotherapy drugs (nivolumab alone or with ipilimumab) after melanoma surgery can prevent the cancer from coming back. 67 adults with stage III melanoma that can be removed by surgery will receive one dose of nivolumab before surgery, then contin…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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New combo aims to unleash immune system on tough melanoma
Disease control OngoingThis early-stage study tests a new drug, SX-682, in people with advanced melanoma that has spread. The drug is designed to block cancer from hiding from the immune system. Participants first take SX-682 alone, then add the immunotherapy pembrolizumab for up to two years. The goal…
Matched conditions: MELANOMA STAGE III
Phase: PHASE1 • Sponsor: Syntrix Biosystems, Inc. • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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New drug combo shows promise in shrinking melanoma before surgery
Disease control OngoingThis study tests whether giving two drugs, pembrolizumab and lenvatinib, before surgery can help shrink tumors in people with stage III melanoma that can be removed. About 21 adults with resectable stage III melanoma will receive the drugs for 6 weeks, then have surgery to remove…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Melanoma Institute Australia • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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New combo therapy aims to shrink melanoma before surgery
Disease control OngoingThis study tests whether giving immunotherapy drugs before surgery can shrink advanced melanoma (stage III or IV) that can be removed. About 48 adults will receive either one drug (dostarlimab) or two drugs (dostarlimab plus cobolimab) before their operation. The main goal is to …
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Diwakar Davar • Aim: Disease control
Last updated May 06, 2026 16:13 UTC
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New PET scan may predict immunotherapy success in melanoma
Disease control OngoingThis study tests whether giving a combination of two immunotherapy drugs (nivolumab and ipilimumab) before surgery can shrink melanoma tumors and prevent the cancer from coming back. About 28 adults with stage III melanoma that can be surgically removed will receive the drugs bef…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New hope for skin cancer patients suffering from severe gut side effects of immunotherapy
Symptom relief OngoingThis study looks at whether infliximab can treat colitis (inflammation of the colon) caused by immunotherapy drugs in people with advanced skin cancer. About 42 participants will receive either infliximab or steroids to see which works better at stopping symptoms without needing …
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC