ME/CFS
Clinical trials for ME/CFS explained in plain language.
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Hope for ME/CFS and long COVID: new drug combo trial launches
Disease control Recruiting nowThis study tests two drugs—pyridostigmine (Mestinon) and low-dose naltrexone (LDN)—alone or together in 160 adults with ME/CFS or Long COVID who also have orthostatic intolerance (difficulty standing). Over 3 months, participants take gradually increasing doses and complete exerc…
Matched conditions: ME/CFS
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Fatigue study seeks to unravel mystery of exhaustion
Knowledge-focused Recruiting nowThis study aims to better understand fatigue by comparing people who have felt tired for more than a month with those who are not fatigued. Researchers will use questionnaires, physical tests, and optional brain scans to identify different types of fatigue. The goal is to gather …
Matched conditions: ME/CFS
Sponsor: National Center for Complementary and Integrative Health (NCCIH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Housebound no more: new study brings doctors to the bedside of ME/CFS patients
Knowledge-focused Recruiting nowThis study focuses on people with ME/CFS or Long COVID who are too sick to leave home. Researchers will provide monthly in-home medical visits and create personalized care plans. The goal is to see if this approach improves patients' health and eases the burden on their caregiver…
Matched conditions: ME/CFS
Phase: NA • Sponsor: Hannover Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Massive study aims to unlock secrets of brain inflammation diseases
Knowledge-focused Recruiting nowThis research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…
Matched conditions: ME/CFS
Sponsor: Brain Inflammation Collaborative • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC