MALIGNANT NEOPLASMS
Clinical trials for MALIGNANT NEOPLASMS explained in plain language.
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New pill combo takes on Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage trial tests two experimental pills (PF-07799544 and PF-07799933) taken twice daily at home by adults with advanced solid tumors that have a specific gene change called BRAF V600. The study aims to find safe doses and see if the drugs can shrink tumors. About 124 …
Matched conditions: MALIGNANT NEOPLASMS
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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New pill for Hard-to-Treat cancers enters first human tests
Disease control Recruiting nowThis early-stage study tests a new oral drug, DEG6498, in about 100 adults with advanced solid tumors that have not responded to standard treatments. The main goals are to find a safe dose and understand side effects. Participants take the drug once daily and are closely monitore…
Matched conditions: MALIGNANT NEOPLASMS
Phase: PHASE1 • Sponsor: Degron Therapeutics Co. • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New combo therapy aims to shrink kidney tumors in Late-Stage trial
Disease control Recruiting nowThis study tests whether adding the experimental drug SLC-3010 to the standard drug axitinib works better than axitinib alone for people with advanced clear cell kidney cancer that has worsened after first treatment. About 78 adults will be randomly assigned to one of the two gro…
Matched conditions: MALIGNANT NEOPLASMS
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Scientists bank tumors and blood to unlock cancer secrets
Knowledge-focused Recruiting nowThis study collects blood, urine, saliva, and tissue samples from nearly 6,000 people who have or may have cancer, including rare inherited forms. The samples are stored and used for research to understand the genetic and molecular basis of cancer. No new treatment is being teste…
Matched conditions: MALIGNANT NEOPLASMS
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New study aims to uncover why some women have worse sexual side effects from radiation
Knowledge-focused Recruiting nowThis study is observing 300 women with female sexual organs who are receiving radiotherapy for certain cancers. Researchers want to understand why some patients have more sexual side effects than others. They will track sexual quality of life and look at radiation doses to find p…
Matched conditions: MALIGNANT NEOPLASMS
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC