LOCALLY ADVANCED PANCREATIC CARCINOMA
Clinical trials for LOCALLY ADVANCED PANCREATIC CARCINOMA explained in plain language.
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New drug combo aims to shrink Hard-to-Treat tumors
Disease control Recruiting nowThis study tests two experimental drugs, ZEN003694 and entinostat, in people with advanced solid tumors that have stopped responding to standard treatments. The goal is to find the safest dose and see if the combination can shrink tumors. The trial includes up to 49 participants,…
Matched conditions: LOCALLY ADVANCED PANCREATIC CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 02:17 UTC
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New cocktail of targeted drug, immunotherapy, and radiation takes on tough pancreatic cancer
Disease control Recruiting nowThis early-stage trial tests whether combining a targeted drug (olaparib), an immunotherapy (durvalumab), and radiation therapy is safe for people with locally advanced pancreatic cancer that cannot be surgically removed. About 18 participants will receive the combination after i…
Matched conditions: LOCALLY ADVANCED PANCREATIC CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for advanced cancers with DNA repair flaws: PARP inhibitor trial opens
Disease control Recruiting nowThis study tests the drug talazoparib in adults with advanced solid tumors (like breast, prostate, ovarian, pancreatic, or stomach cancer) that have certain gene changes affecting DNA repair. The drug blocks a protein called PARP, which cancer cells need to fix their DNA, potenti…
Matched conditions: LOCALLY ADVANCED PANCREATIC CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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Scientists track tumor changes during chemoradiation in cervical and pancreatic cancers
Knowledge-focused Recruiting nowThis study aims to understand how the tumor's surroundings change during chemoradiotherapy for locally advanced cervical and pancreatic cancers. Researchers will collect tissue samples, blood, and imaging data from 60 participants before, during, and after treatment. The goal is …
Matched conditions: LOCALLY ADVANCED PANCREATIC CARCINOMA
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Apr 26, 2026 19:37 UTC