LOCALLY ADVANCED OR METASTATIC SOLID TUMORS
Clinical trials for LOCALLY ADVANCED OR METASTATIC SOLID TUMORS explained in plain language.
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New drug duo targets Hard-to-Treat cancers in phase 2 trial
Disease control Not yet recruitingThis study tests a combination of two experimental drugs (GH21 and D-1553) in 120 adults with advanced solid tumors that have a specific genetic change called KRASG12C. Participants must have already tried standard treatments or have no standard options, and have previously taken…
Matched conditions: LOCALLY ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE2 • Sponsor: Suzhou Genhouse Bio Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 11:51 UTC
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New drug combo aims to shrink Hard-to-Treat tumors
Disease control Not yet recruitingThis study tests a new drug called BC3195 combined with pembrolizumab in people with advanced solid tumors that have spread. The goal is to find a safe dose and see if the combination can shrink tumors. About 111 adults with certain cancers will take part.
Matched conditions: LOCALLY ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Biocity Biopharmaceutics Co., Ltd. • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for Hard-to-Treat cancers: drug combo targets PTEN loss
Disease control Not yet recruitingThis study tests a combination of two drugs (CVL237 and serplulimab) in people with advanced solid tumors that have lost or have low levels of a protein called PTEN. The goal is to see if this treatment can shrink tumors or slow their growth. About 180 adults whose cancer has wor…
Matched conditions: LOCALLY ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE2 • Sponsor: Convalife (Shanghai) Co., Ltd. • Aim: Disease control
Last updated May 12, 2026 13:43 UTC