LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Clinical trials for LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA explained in plain language.
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Could a common heart drug boost cancer treatment?
Disease control Recruiting nowThis study tests whether adding propranolol (a beta-blocker used for heart conditions) to standard chemotherapy and immunotherapy can help people with advanced esophageal or stomach cancer that cannot be surgically removed. The drug may reduce stress hormones that can weaken the …
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 17, 2026 04:32 UTC
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New drug combo targets Hard-to-Treat HER2 cancers in early trial
Disease control Recruiting nowThis early-phase study tests a combination of two drugs (trastuzumab deruxtecan and azenosertib) in people with HER2-positive stomach, gastroesophageal junction, or other solid tumors that have spread or cannot be removed by surgery. The main goals are to find the safest dose and…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 04:15 UTC
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New combo drug trial hopes to shrink tough cancers
Disease control Recruiting nowThis early-stage study tests a new combination of two drugs (trifluridine/tipiracil and talazoparib) in people with advanced colorectal or gastroesophageal cancers that have spread. The main goals are to find the safest dose and understand side effects. About 45 participants will…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Tailor-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors. The goal is to see if this combination is safe and helps the immune system fight cancer more effectively. A…
Matched conditions: LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 14, 2026 12:02 UTC