LARGE B-CELL LYMPHOMA (LBCL)
Clinical trials for LARGE B-CELL LYMPHOMA (LBCL) explained in plain language.
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Affordable CAR-T breakthrough: academic therapy offers new hope for blood cancer patients
Disease control Recruiting nowThis study is testing a more affordable version of CAR-T cell therapy for people with relapsed or hard-to-treat large B-cell lymphoma. The treatment uses the patient's own immune cells, modified to attack cancer cells. The goal is to see if this academic-made therapy works as wel…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Sponsor: N.N. Alexandrov National Cancer Centre • Aim: Disease control
Last updated Jun 17, 2026 06:27 UTC
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New hope for hard-to-treat lymphoma: experimental drug enters phase 2 trial
Disease control Recruiting nowThis study tests a new drug called surovatamig (AZD0486) in adults with B-cell non-Hodgkin lymphoma that has come back or stopped responding to at least two prior treatments. The goal is to see if the drug can shrink or eliminate tumors. About 240 participants will receive the dr…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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New combo aims to supercharge Cancer-Fighting cells in lymphoma patients
Disease control Recruiting nowThis early-stage study tests whether adding an experimental drug called CLS-015 to standard CAR-T cell therapy can improve outcomes for people with large B-cell lymphoma whose cancer has not responded well. The drug aims to reverse immune-suppressing effects in the tumor environm…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE1 • Sponsor: Tel-Aviv Sourasky Medical Center • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Immune cell therapy shows promise for aggressive blood cancer
Disease control Recruiting nowThis study tests a treatment called CD19 CAR-T therapy for people newly diagnosed with a fast-growing type of blood cancer called high-risk large B-cell lymphoma. The therapy uses a patient's own immune cells, which are modified in a lab to better find and kill cancer cells. The …
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New hope for older lymphoma patients: drug combo targets cancer without harsh chemo
Disease control Recruiting nowThis study tests a combination of four drugs (Pola-ZR-Glo) in older adults (70+) newly diagnosed with large B-cell lymphoma who cannot tolerate standard chemotherapy. The goal is to control the disease and improve quality of life. About 30 participants will receive the treatment …
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC