KIDNEY FAILURE, CHRONIC

This early-stage study tested a single injection of an experimental drug called MK-2060 in people with advanced kidney disease. The main goals were to check the drug's safety, see how long it stays in the body, and measure its effect on blood clotting. Only 14 people with stage 4…

This study compared two anesthesia methods for creating dialysis access in patients with advanced kidney failure. Researchers tested whether a regional nerve block (axillary block) leads to fewer early complications than standard local anesthesia. The goal was to determine which …

This study tested whether stable patients on dialysis who still have some of their own kidney function could safely receive treatment twice a week instead of the standard three times. It involved 58 patients who tried both schedules for four weeks each. Researchers measured treat…

This study tested whether a non-invasive urine test could predict dangerous scarring in transplanted kidneys. Researchers followed 300 kidney transplant patients for a year, analyzing genetic markers in their urine. The goal was to see if this test could accurately identify patie…

This study tested whether an experimental drug called MK-2060 could prevent dangerous blood clots from forming in the artificial grafts used for dialysis in people with kidney failure. Over 500 participants received either one of two doses of the drug or a placebo to see which wo…

This large European study aimed to see if regularly checking and refreshing patients' knowledge and skills for performing home peritoneal dialysis could prevent serious abdominal infections called peritonitis. It involved 713 new dialysis patients who could perform their treatmen…

This study tested whether a special communication tool called 'Best Case/Worst Case' helps doctors have better conversations with older patients who have severe, permanent kidney failure. The tool helps doctors and patients talk about future care options, quality of life, and end…

This study aimed to understand how the experimental drug MK-5684 is processed by the body in men with severe or end-stage kidney disease. Researchers compared drug levels in the blood of 24 men—some with kidney disease and some healthy—after a single dose. The goal was to see if …

This early-stage study tested how a single dose of an experimental drug, BMS-986278, is processed by the body in people with different levels of kidney function. It involved 27 participants, including healthy volunteers and people with severe kidney disease or kidney failure requ…