KERATOCONUS

This study tests whether a procedure called corneal collagen crosslinking can stop keratoconus from getting worse. Keratoconus is a condition where the cornea (the clear front part of the eye) becomes thin and bulges into a cone shape, causing blurry vision. The treatment uses sp…

This early-stage trial tests TN-001 eyedrops in 20 adults with progressive keratoconus, a condition that thins and bulges the cornea. Participants use the drops twice daily for 3-6 weeks. The main goals are to check safety and see if the drops can stop the disease from advancing.

This study compares an artificial intelligence (AI) system called AEYE to a human eye doctor in diagnosing keratoconus, a condition that can make laser eye surgery risky. Researchers will use 50 real patient cases to see if the AI can match or beat the doctor's accuracy. If succe…

This study tests if a tiny steroid implant placed in the tear duct works as well as standard steroid eye drops for managing inflammation after corneal crosslinking surgery for keratoconus. About 20 people aged 13 and older with progressive keratoconus will be enrolled. The implan…

This study looks at how electrical signals in the eyes change as keratoconus gets worse. Researchers will test 50 people aged 18 to 40 with different stages of the disease. They use special light tests to measure how the retina and brain respond, which may help doctors predict vi…

This study uses a special light-based technique called Brillouin microscopy to measure how stiff or weak the cornea is in people with keratoconus, a condition that thins and bulges the cornea. Researchers will also look at how the cornea changes after treatments like cross-linkin…