ISOCITRATE DEHYDROGENASE GENE MUTATION
Clinical trials for ISOCITRATE DEHYDROGENASE GENE MUTATION explained in plain language.
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Experimental IDH drug trial halted early
Disease control TerminatedThis early-stage study tested a new drug, HMPL-306, in 42 adults with advanced solid tumors that have an IDH mutation. The goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited and no cure is expected.
Matched conditions: ISOCITRATE DEHYDROGENASE GENE MUTATION
Phase: PHASE1 • Sponsor: Hutchmed • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Experimental IDH drug trial halted early – what we know so far
Disease control TerminatedThis early-stage study tested an experimental drug called HMPL-306 in 46 adults with advanced blood cancers (like leukemia) that have a specific genetic change called an IDH mutation. The goal was to find a safe dose and check for side effects. The study was stopped early, so res…
Matched conditions: ISOCITRATE DEHYDROGENASE GENE MUTATION
Phase: PHASE1 • Sponsor: Hutchmed • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC