Experimental IDH drug trial halted early
NCT ID NCT04762602
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This early-stage study tested a new drug, HMPL-306, in 42 adults with advanced solid tumors that have an IDH mutation. The goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited and no cure is expected.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Emory University
Atlanta, Georgia, 30322, United States
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital de la Santa creu i Sant Pau
Barcelona, 08025, Spain
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Houston Methodist
Houston, Texas, 77030, United States
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Sarcoma Oncology Research Center
Santa Monica, California, 90403, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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UPMC Hillman Cancer
Pittsburgh, Pennsylvania, 15232, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of Kentucky
Lexington, Kentucky, 40536, United States