INVASIVE CANDIDIASIS
Clinical trials for INVASIVE CANDIDIASIS explained in plain language.
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Blood biomarkers may let ICU patients stop antifungals earlier
Disease control CompletedThis study tested whether using blood biomarkers (beta-D-glucan and mannan) can help doctors safely stop antifungal drugs earlier in critically ill patients suspected of a fungal infection. 192 ICU patients were randomly assigned to either a biomarker-guided strategy or standard …
Matched conditions: INVASIVE CANDIDIASIS
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New blood tests could speed up detection of deadly fungal infections
Diagnosis CompletedThis study looked at whether combining several blood tests can detect serious fungal infections (candidemia) faster and more accurately than standard methods. Researchers tested 2 hospitalized adults with suspected fungal infections using both routine blood cultures and newer tes…
Matched conditions: INVASIVE CANDIDIASIS
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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Blood test may speed up deadly fungal infection diagnosis
Diagnosis CompletedThis study looked at a blood test called Beta-D-glucan (BDG) to see how well it detects invasive fungal infections in people with weak immune systems. Researchers tested 280 patients and checked if two positive results within 15 days confirmed an infection. The goal is to help do…
Matched conditions: INVASIVE CANDIDIASIS
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New drug could shield transplant patients from deadly fungal infections
Prevention CompletedThis study tested a new medicine called rezafungin to see if it can prevent serious fungal infections in adults getting a bone marrow transplant. About 600 participants received either rezafungin or the standard treatment. The goal was to see if rezafungin helps more people stay …
Matched conditions: INVASIVE CANDIDIASIS
Phase: PHASE3 • Sponsor: Mundipharma Research Limited • Aim: Prevention
Last updated Jun 27, 2026 12:07 UTC
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Study questions unnecessary antifungal use in intensive care
Knowledge-focused CompletedThis study looked at whether it's safe to reduce or stop antifungal drugs early in immunocompromised ICU patients suspected of having a fungal infection. Researchers tracked 275 patients across 14 ICUs to see how often doctors de-escalated treatment and what factors influenced th…
Matched conditions: INVASIVE CANDIDIASIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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ICU patients may need custom doses of common antifungal
Knowledge-focused CompletedThis study looked at how the antifungal drug micafungin is processed in the bodies of 60 critically ill ICU patients with invasive candidiasis. Researchers took multiple blood samples to measure drug levels and understand why some patients might not get enough medicine. The goal …
Matched conditions: INVASIVE CANDIDIASIS
Phase: PHASE4 • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC