IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Clinical trials for IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION explained in plain language.
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Can bosentan reverse lung artery thickening? small study investigates
Disease control CompletedThis study looked at whether bosentan (Tracleer) can reduce the thickness of lung artery walls in people with a type of high blood pressure in the lungs (pulmonary arterial hypertension, or PAH). Eleven adults with PAH took bosentan for 6 months. Researchers measured artery wall …
Matched conditions: IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Phase: PHASE4 • Sponsor: Actelion • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Small study aims to unlock secrets of rare lung disease
Knowledge-focused CompletedThis completed Phase 1 study looked at 27 people with and without pulmonary hypertension to learn more about how blood vessel problems contribute to the disease. Researchers used heart catheterization, imaging, and blood tests to find biomarkers and understand disease mechanisms.…
Matched conditions: IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Phase: PHASE1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Immune clues in rare lung disease explored
Knowledge-focused CompletedThis completed study looked at how the immune system might affect the outlook for people with pulmonary arterial hypertension (PAH). Researchers took blood and skin samples from 629 participants with different types of PAH to search for specific antibodies. The goal was to better…
Matched conditions: IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Researchers dive into why scleroderma and lung hypertension weaken the heart
Knowledge-focused CompletedThis study looked at 43 adults with scleroderma or unexplained pulmonary arterial hypertension (PAH) to understand why the right side of the heart weakens. Researchers collected blood and tissue samples during routine procedures and measured heart function over 6 months. The goal…
Matched conditions: IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC