HYPOSMIA
Clinical trials for HYPOSMIA explained in plain language.
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New drug aims to restore lost smell in clinical trial
Symptom relief CompletedThis study tested a new drug called CYR-064 in 151 adults aged 18-70 who have a reduced sense of smell (hyposmia). The goal was to see if the drug is safe and if it can improve smell and taste over 24 weeks compared to a placebo. Participants had no other nasal issues like polyps…
Matched conditions: HYPOSMIA
Phase: PHASE2 • Sponsor: Cyrano Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Neck injection may restore smell in long COVID patients
Symptom relief CompletedThis pilot study tested whether a stellate ganglion block—a numbing injection near a nerve cluster in the neck—can help people who lost their sense of smell after COVID-19. Twenty adults with smell problems lasting at least a year received the injection. Researchers measured chan…
Matched conditions: HYPOSMIA
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Could scented nose plugs be the key to restoring lost smell?
Symptom relief CompletedThis study tested whether scented nose plugs could make smell training more effective for people who lost their sense of smell after a virus like COVID-19. 120 adults with reduced smell were split into two groups: one did regular smell training at home, and the other used scented…
Matched conditions: HYPOSMIA
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Jun 26, 2026 12:46 UTC
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Could your nose warn of a rare heart disease?
Knowledge-focused CompletedThis study checked how common smell and taste problems are in 51 people with cardiac amyloidosis, a rare disease where abnormal proteins build up in the heart. Researchers used a simple smell test called Sniffin' Sticks to measure these senses. The goal was to see if these issues…
Matched conditions: HYPOSMIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC