HYPOPHOSPHATASIA
Clinical trials for HYPOPHOSPHATASIA explained in plain language.
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Scientists track rare bone disease to unlock future treatments
Knowledge-focused Recruiting nowThis study aims to better understand hypophosphatasia, a rare genetic disorder that affects bone and tooth development. Researchers will follow 200 children and adults with this condition over time to document how symptoms progress, how treatments work, and how the disease affect…
Matched conditions: HYPOPHOSPHATASIA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 02, 2026 00:26 UTC
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Scientists track rare bone disease patients for 5 years to see if treatment stops working
Knowledge-focused Recruiting nowThis study aims to understand if the immune system of patients with a rare bone disease, hypophosphatasia, can stop their main treatment, asfotase alfa, from working or cause severe allergic reactions. It will follow about 30 patients, including children and adults, for at least …
Matched conditions: HYPOPHOSPHATASIA
Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Scientists map the hidden journey of a rare bone disease
Knowledge-focused Recruiting nowThis study aims to better understand how a specific genetic change affects the symptoms and progression of hypophosphatasia (HPP), a rare bone and mineral disorder. Researchers will observe 55 children and adults in Russia who have this genetic variant but are not receiving speci…
Matched conditions: HYPOPHOSPHATASIA
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Rare bone disease registry seeks to solve diagnosis delays
Knowledge-focused Recruiting nowThis study is creating a long-term registry to track adults with hypophosphatasia, a rare genetic bone disease. Researchers will follow 130 patients to better understand their symptoms, how long it takes to get diagnosed, and how they respond to treatments. The goal is to improve…
Matched conditions: HYPOPHOSPHATASIA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC