HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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Could a chemo drug boost radiation for head and neck cancer survivors?
Disease control Recruiting nowThis study compares radiation therapy alone versus radiation plus the chemotherapy drug cisplatin in people with stage III-IVA head and neck cancer who have already had surgery to remove their tumor. About 189 participants will be randomly assigned to one of the two treatments. T…
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 11:51 UTC
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Could less radiation be safer? new trial aims to shrink treatment zones without raising cancer return risk
Disease control Recruiting nowThis study tests whether giving radiation only to high-risk areas after surgery for head and neck cancer can lower side effects without increasing the chance of cancer coming back. About 50 adults with certain types of head and neck cancer will receive a personalized radiation pl…
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Olgun Elicin • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New drug combo aims to spare voice box in advanced throat cancer
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy can help control advanced laryngeal or hypopharyngeal cancer while avoiding removal of the voice box (laryngectomy). About 87 adults with stage III-IV disease that is surgically removable …
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Matthew Spector • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Could a Two-Drug punch before surgery beat head and neck cancer?
Disease control Recruiting nowThis study tests whether adding an experimental drug (CDX-1140) to a standard immunotherapy (cemiplimab) before surgery can shrink advanced head and neck cancers more than the immunotherapy alone. About 44 people with stage III-IV head and neck cancer will receive either the comb…
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New drug aims to ease painful mouth sores for head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether adding BMX-001 to standard care can reduce severe mouth sores caused by chemoradiation in head and neck cancer patients. About 98 participants will receive either BMX-001 or a placebo alongside their usual treatment. The goal is to improve quality of life…
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 17, 2026 11:52 UTC
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New imaging study reveals hidden vascular damage from radiation in head and neck cancer
Knowledge-focused Recruiting nowThis study uses special PET/CT scans to see how radiation therapy affects blood vessels in the neck of people with head and neck cancers. About 20 adults will get two types of PET scans before and after radiation. The goal is to compare the scans and learn more about radiation's …
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Remote hearing tests could save cancer Patients' hearing
Knowledge-focused Recruiting nowThis study looks at whether offering hearing tests close to home or remotely can help more head and neck cancer patients get their hearing checked during and after treatment. Many patients on cisplatin chemotherapy or radiation may lose hearing, but traveling to the clinic for te…
Matched conditions: HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC