HYPERTENSION, PULMONARY
Clinical trials for HYPERTENSION, PULMONARY explained in plain language.
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Blood pressure drug shows Long-Term safety in rare lung condition
Disease control CompletedThis study followed 18 adults with pulmonary arterial hypertension (PAH) who had already taken riociguat in earlier trials. Researchers wanted to see if the drug remained safe and tolerable over a longer period. The goal was to keep providing treatment until it was no longer help…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE4 • Sponsor: Bayer • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New drug shows promise for hard-to-treat lung-heart condition
Disease control CompletedThis study tested a drug called sotatercept in 164 adults with a specific type of pulmonary hypertension caused by heart failure. The goal was to see if it improves blood flow in the lungs and walking ability compared to a placebo. Participants received either the drug or a place…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE2 • Sponsor: Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New PAH pill aims to keep patients out of hospital
Disease control CompletedThis study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Blood test could spot hidden lung disease before It's too late
Diagnosis CompletedThis study looked for special markers in the blood that could help doctors find pulmonary hypertension (high blood pressure in the lungs) earlier. Over 900 adults took part, and researchers compared the blood test results to the standard diagnosis method (a heart catheterization)…
Matched conditions: HYPERTENSION, PULMONARY
Phase: EARLY_PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Diagnosis
Last updated May 13, 2026 16:00 UTC
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Inflammation markers studied in kids with heart defects and lung hypertension
Knowledge-focused CompletedThis study looked at whether a specific inflammatory protein, HMGB1, is higher in children with congenital heart disease and pulmonary hypertension compared to those with heart disease alone or healthy children. Researchers measured blood samples from 74 children during heart cat…
Matched conditions: HYPERTENSION, PULMONARY
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC