HYPERTENSION, PULMONARY
Clinical trials for HYPERTENSION, PULMONARY explained in plain language.
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New PAH pill aims to delay worsening in large trial
Disease control CompletedThis study tested a new oral drug called ralinepag in 687 adults with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work harder. Participants took ralinepag or a placebo on top of their usual PAH medications. The main goal was to see if rali…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a natural hormone help COPD patients breathe easier?
Disease control CompletedThis study tested whether a natural hormone called DHEA can improve exercise ability in adults with COPD and high blood pressure in the lungs. 51 participants took either a low or high dose of DHEA or a placebo daily for one year. The main goal was to see if DHEA helped them walk…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Could a hormone supplement ease lung pressure in COPD?
Disease control CompletedThis study tested whether a daily dose of the hormone DHEA can help adults with COPD who also have high blood pressure in their lungs. Sixty participants took either DHEA or a placebo for one year. Researchers measured how far they could walk in six minutes and checked heart and …
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Can bosentan reverse lung artery thickening? small study investigates
Disease control CompletedThis study looked at whether bosentan (Tracleer) can reduce the thickness of lung artery walls in people with a type of high blood pressure in the lungs (pulmonary arterial hypertension, or PAH). Eleven adults with PAH took bosentan for 6 months. Researchers measured artery wall …
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE4 • Sponsor: Actelion • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New drug shows promise for Hard-to-Treat lung condition in heart failure
Disease control CompletedThis Phase 2 trial tested a drug called sotatercept in 164 adults with a type of high blood pressure in the lungs caused by heart failure. The study compared sotatercept to a placebo to see if it could improve blood flow and walking distance. The goal is to find a better treatmen…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE2 • Sponsor: Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Blood pressure drug riociguat tested for Long-Term use in rare lung condition
Disease control CompletedThis study looked at the long-term safety of the drug riociguat (Adempas) in adults with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. It included 18 people who had already taken riociguat in earlier Bayer studies. The main goal was to track s…
Matched conditions: HYPERTENSION, PULMONARY
Phase: PHASE4 • Sponsor: Bayer • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a simple blood test catch lung hypertension early?
Diagnosis CompletedThis completed study looked for specific molecules in the blood (called microRNAs) that could help detect pulmonary hypertension (PH) early. Researchers analyzed blood samples from 907 participants who had or were scheduled for a right heart catheterization, the standard diagnost…
Matched conditions: HYPERTENSION, PULMONARY
Phase: EARLY_PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Diagnosis
Last updated Jun 26, 2026 16:39 UTC
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Inflammation clues found in kids with rare lung condition
Knowledge-focused CompletedThis study measured levels of an inflammatory protein called HMGB1 in 74 children with congenital heart disease and pulmonary hypertension. Researchers compared these levels to those in children with heart disease alone and healthy controls. The goal was to see if inflammation pl…
Matched conditions: HYPERTENSION, PULMONARY
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC