HNSCC
Clinical trials for HNSCC explained in plain language.
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Could a short course of abemaciclib shrink head and neck tumors?
Disease control TerminatedThis phase II trial tested the drug abemaciclib in 7 people with HPV-negative head and neck cancer. Participants took the drug for 10 to 28 days before their planned surgery. The goal was to see if the drug could shrink tumors and to check for side effects. The study was terminat…
Matched conditions: HNSCC
Phase: PHASE2 • Sponsor: University of Arizona • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Experimental combo for head and neck cancer shows promise, but trial halted early
Disease control TerminatedThis Phase 2 trial tested whether adding danvatirsen to the standard immunotherapy pembrolizumab helps people with recurrent or metastatic head and neck squamous cell carcinoma. About 69 adults with PD-L1 positive tumors were randomly assigned to receive the combination or pembro…
Matched conditions: HNSCC
Phase: PHASE2 • Sponsor: Flamingo Therapeutics NV • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC