HIGH-RISK NEUROBLASTOMA
Clinical trials for HIGH-RISK NEUROBLASTOMA explained in plain language.
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Engineered immune cells take aim at childhood cancer
Disease control OngoingThis early-stage trial is testing a new type of cell therapy for children with neuroblastoma that has returned or is hard to treat. The therapy uses the patient's own immune cells, which are modified in the lab to recognize and attack a protein called PHOX2B found on neuroblastom…
Matched conditions: HIGH-RISK NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Stephan Grupp MD PhD • Aim: Disease control
Last updated Jul 02, 2026 04:00 UTC
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New vaccine aims to train immune system to attack childhood cancer
Disease control OngoingThis trial tests a vaccine designed to help the immune system recognize and attack neuroblastoma, a type of childhood cancer. The vaccine contains two antigens found on neuroblastoma cells, plus an adjuvant to boost the immune response. Participants also take an oral supplement c…
Matched conditions: HIGH-RISK NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Promising new drug combo gives hope for kids with relapsed neuroblastoma
Disease control OngoingThis study tests whether adding eflornithine (DFMO) to a standard chemotherapy and immunotherapy regimen can improve outcomes for children with neuroblastoma that has returned or is not responding to treatment. About 94 children will be randomly assigned to receive the standard t…
Matched conditions: HIGH-RISK NEUROBLASTOMA
Phase: PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New hope for kids with tough cancer: drug may keep neuroblastoma at bay
Disease control OngoingThis study tests whether the drug eflornithine, taken as a pill after immunotherapy, can help prevent high-risk neuroblastoma from coming back in children. Twenty children under 18 who have completed standard treatment will take eflornithine for maintenance. Researchers will trac…
Matched conditions: HIGH-RISK NEUROBLASTOMA
Sponsor: Shanghai Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can we spot late side effects in neuroblastoma survivors? new study aims to find out
Knowledge-focused OngoingThis study looks at whether it's possible to screen for long-term health problems in people who survived high-risk neuroblastoma. Researchers will evaluate survivors who finished treatment at least 2 years ago, using tests for heart, nerve, and other health issues. The goal is to…
Matched conditions: HIGH-RISK NEUROBLASTOMA
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC