HIGH-GRADE SEROUS OVARIAN CARCINOMA
Clinical trials for HIGH-GRADE SEROUS OVARIAN CARCINOMA explained in plain language.
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Custom-Made vaccine takes on ovarian cancer
Disease control CompletedThis Phase 1 trial tested a personalized immunotherapy called TG4050 in 64 women with advanced ovarian, fallopian tube, or peritoneal cancer who had completed standard chemotherapy and were in complete remission. The treatment is made from each patient's unique tumor mutations an…
Matched conditions: HIGH-GRADE SEROUS OVARIAN CARCINOMA
Phase: PHASE1 • Sponsor: Transgene • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Ovarian cancer hope: new combo shows promise in shrinking tumors before surgery
Disease control CompletedThis phase 2 trial tested whether adding an experimental drug (MK-4830) to standard chemotherapy and pembrolizumab (Keytruda) could better shrink high-grade serous ovarian cancer before surgery. 160 participants with stage III or IV disease received either the standard regimen or…
Matched conditions: HIGH-GRADE SEROUS OVARIAN CARCINOMA
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New drug combo shows promise against resistant ovarian cancer
Disease control CompletedThis Phase 2 trial tested whether adding afuresertib (an AKT inhibitor) to standard paclitaxel chemotherapy helps control platinum-resistant ovarian cancer better than paclitaxel alone. 150 women with this difficult-to-treat cancer participated. The study measured how long the ca…
Matched conditions: HIGH-GRADE SEROUS OVARIAN CARCINOMA
Phase: PHASE2 • Sponsor: Laekna Limited • Aim: Disease control
Last updated Jun 26, 2026 15:45 UTC
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Routine BRCA testing for ovarian cancer patients proves feasible in irish study
Knowledge-focused CompletedThis study tested whether it is practical to routinely check ovarian cancer tumors for BRCA gene mutations in the clinic. Researchers enrolled 200 patients with high-grade serous or endometrioid ovarian, fallopian tube, or primary peritoneal cancer. They used blood and tumor samp…
Matched conditions: HIGH-GRADE SEROUS OVARIAN CARCINOMA
Sponsor: Cancer Trials Ireland • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC