HIE
Clinical trials for HIE explained in plain language.
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Could a common asthma drug shield newborns from kidney damage?
Disease control OngoingThis early study tests whether the drug theophylline can prevent kidney injury in newborns who experienced oxygen deprivation at birth (HIE) and are receiving cooling therapy. Thirty infants will receive one or two doses of theophylline within 18 hours of birth. The main goal is …
Matched conditions: HIE
Phase: PHASE1, PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Diabetes drug could help Babies' brains heal after birth injury
Disease control ENROLLING_BY_INVITATIONThis early-stage trial tests whether metformin, a common diabetes drug, is safe and feasible for infants who suffered brain injury from lack of oxygen at birth. Thirty infants under 6 months old will receive metformin for 6 weeks, with close monitoring of kidney and liver functio…
Matched conditions: HIE
Phase: PHASE1 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC