HER2 POSITIVE BREAST CARCINOMA
Clinical trials for HER2 POSITIVE BREAST CARCINOMA explained in plain language.
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Scientists test Patient-Made vaccine to train immune system against breast cancer
Disease control OngoingThis early-phase study is testing a personalized vaccine for people with HER2-positive breast cancer. The vaccine is made from the patient's own immune cells and is designed to teach the body's immune system to attack the cancer. Researchers are giving the vaccine alongside stand…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New combo therapy trial offers hope for Tough-to-Treat breast cancer
Disease control OngoingThis study is testing whether adding a pill called niraparib to the standard IV drug trastuzumab is safe and effective for people with advanced HER2-positive breast cancer that has spread. It's for patients whose cancer has grown despite previous HER2-targeted treatments. The mai…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New hope for Tough-to-Treat breast cancer
Disease control OngoingThis study is testing whether adding a new experimental drug, TVB-2640, to standard treatments can help control advanced HER2-positive breast cancer that has spread and is no longer responding to the usual therapies. It involves a small group of patients whose cancer has progress…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New hope for High-Risk breast cancer patients: can two drugs beat one?
Disease control OngoingThis large study is testing whether adding the drug tucatinib to standard treatment (T-DM1) works better at preventing breast cancer from coming back. It is for people with a specific type of high-risk, HER2-positive breast cancer who still have some cancer cells after their init…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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New scan could tell doctors if breast cancer treatment is working sooner
Diagnosis OngoingThis study is testing a special imaging scan (FDG-PET/CT) to see if it can predict how well standard chemotherapy works for patients with HER2-positive breast cancer before they have surgery. The scan is done early in treatment to measure changes in the cancer's activity. If succ…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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New scan could tell doctors if breast cancer drugs will work before surgery
Diagnosis OngoingThis study is testing a special PET scan to see if it can predict how well a patient's HER2-positive breast cancer will respond to two targeted drugs (trastuzumab and pertuzumab) given before surgery. Researchers will give 18 patients with locally advanced breast cancer a scan us…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Mar 30, 2026 14:29 UTC
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Vaccine trial aims to stop aggressive breast Cancer's return
Prevention OngoingThis study is testing two different vaccines designed to prevent breast cancer from returning in patients with HER2-positive disease. It focuses on people who still had cancer cells remaining after completing their initial chemotherapy and targeted therapy. Researchers will monit…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Prevention
Last updated Mar 27, 2026 12:40 UTC
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Blood test aims to predict breast Cancer's return
Knowledge-focused TerminatedThis study is testing a blood test that looks for tiny pieces of leftover cancer DNA after treatment for early-stage breast cancer. The goal is to see if this test can identify patients who still have hidden cancer cells and might benefit from additional therapy. Researchers will…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Scientists probe how new cancer drug battles tumors
Knowledge-focused OngoingThis is an early, small study to understand how the drug DS-8201a works in the body of patients with advanced HER2-positive cancers. Researchers are giving the drug to 62 patients and taking small tumor samples before and after treatment to see how it affects cancer cells and the…
Matched conditions: HER2 POSITIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC