HER2-NEGATIVE BREAST CARCINOMA
Clinical trials for HER2-NEGATIVE BREAST CARCINOMA explained in plain language.
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New vaccine aims to train immune system against breast cancer stem cells
⭐️ VACCINE ⭐️ OngoingThis early-stage trial tests a DNA vaccine called STEMVAC in 42 people with advanced HER2-negative breast cancer whose disease is stable or gone after standard treatment. The vaccine is designed to help the immune system recognize and attack cancer stem cells, which are often res…
Matched conditions: HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: University of Washington • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:06 UTC
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Shorter radiation course could spare breast appearance in Low-Risk cancer
Disease control OngoingThis phase 2 trial tests whether giving radiation once a day for five days (instead of every other day) can keep the breast looking good after treatment. It includes 48 women aged 40 or older with low-risk, hormone-sensitive breast cancer. The goal is to see if this shorter sched…
Matched conditions: HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Could a lower tamoxifen dose be just as good for Low-Risk breast cancer?
Disease control TerminatedThis phase III trial compares low-dose tamoxifen to standard hormone therapy (aromatase inhibitors) in postmenopausal women with low-risk, hormone-positive, HER2-negative early breast cancer. The goal is to see if the lower dose works just as well to prevent cancer from coming ba…
Matched conditions: HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New combo therapy aims to outsmart resistant breast cancer
Disease control OngoingThis early-stage trial tests a drug called berzosertib combined with radiation therapy for people with certain types of breast cancer that no longer respond to chemotherapy. The goal is to find the safest dose and see if the combination can shrink or stabilize tumors better than …
Matched conditions: HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Texts and talks: a new way to boost breast cancer Pill-Taking
Symptom relief OngoingThis study tests whether text message reminders and phone counseling help women with early-stage breast cancer take their daily hormone therapy pills as prescribed. About 1,167 women will be split into groups: some get usual care, others get texts and/or motivational interviewing…
Matched conditions: HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Jun 26, 2026 15:07 UTC
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Blood test could spot hidden cancer cells after breast cancer surgery
Knowledge-focused TerminatedThis study was designed to see if a blood test that looks for tiny pieces of tumor DNA (called ctDNA) could find leftover cancer cells in people with early-stage breast cancer after standard treatment. The goal was to help doctors decide who might need more therapy. However, the …
Matched conditions: HER2-NEGATIVE BREAST CARCINOMA
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC