HER2 + BREAST CANCER
Clinical trials for HER2 + BREAST CANCER explained in plain language.
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New drug delivery methods tested for tough breast cancer
Disease control Not yet recruitingThis study tests a drug called SHR-A1811 in 60 adults with HER2-positive advanced breast cancer who have had up to 2 prior treatments. Researchers want to see if giving the drug in different ways (like injection or infusion) can shrink tumors. The main goal is to measure how many…
Matched conditions: HER2 + BREAST CANCER
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New biosimilar aims to match phesgo for breast cancer treatment
Disease control Not yet recruitingThis study tests whether a new biosimilar drug, HLX319, works as well as the approved drug Phesgo for people with HER2-positive early or locally advanced breast cancer. About 258 participants will receive either the biosimilar or the original drug before surgery to compare how th…
Matched conditions: HER2 + BREAST CANCER
Phase: PHASE1 • Sponsor: Shanghai Henlius Biotech • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New study tests targeted pill combo for advanced breast cancer in Real-World settings
Disease control Not yet recruitingThis study will follow 500 people with advanced HER2-positive breast cancer who are receiving pyrotinib (a daily pill) as their first or second treatment. Researchers want to see how well the drug works in real life and whether switching to another targeted therapy (Trastuzumab R…
Matched conditions: HER2 + BREAST CANCER
Phase: PHASE4 • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New study aims to spare breast cancer patients from chemo and major surgery
Disease control Not yet recruitingThis study tests a new approach for women with a common type of early breast cancer (HR+/HER2-). Instead of standard chemotherapy before surgery, some participants will receive a combination of hormone therapy and a targeted drug (abemaciclib) based on their tumor's gene test res…
Matched conditions: HER2 + BREAST CANCER
Phase: PHASE2 • Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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New Double-Antibody attack aims to wipe out breast cancer before surgery
Disease control Not yet recruitingThis study tests whether a new drug combination (HLX87 plus HLX22 or pertuzumab) works better than standard chemotherapy before surgery for people with HER2-positive early or locally advanced breast cancer. About 817 participants will be randomly assigned to one of three treatmen…
Matched conditions: HER2 + BREAST CANCER
Phase: PHASE2, PHASE3 • Sponsor: Shanghai Henlius Biotech • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Blood test may reveal if breast cancer treatment is working
Knowledge-focused Not yet recruitingThis study looks at whether tracking tumor DNA in the blood (ctDNA) can help doctors see how well breast cancer treatment is working before surgery. It will include 186 people with stage II-III HER2-positive or triple-negative breast cancer. Researchers will take blood samples at…
Matched conditions: HER2 + BREAST CANCER
Sponsor: Federico II University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC