GENITOURINARY CANCER

This early-stage study is testing the safety of a new two-drug immunotherapy combination, with or without a precise form of radiation, for adults with advanced urinary tract cancers that have spread. The goal is to see if these treatments can work together to help the body's own …

This Canadian study is testing whether a personalized approach to cancer treatment works. It gives the immunotherapy drug atezolizumab to about 200 patients with advanced breast, lung, or other cancers, but only if their tumor's genetic analysis suggests they might respond. The g…

This early-stage trial is testing a two-part personalized treatment for adults with advanced solid cancers that have spread and contain specific KRAS gene mutations. Doctors take a patient's own immune cells, genetically modify them in a lab to recognize and attack cancer cells w…

This study is testing whether a drug called riluzole can help prevent the memory and thinking problems often called 'chemo brain' in people receiving chemotherapy for various cancers. About 24 adult patients will be randomly assigned to receive either riluzole or a placebo pill w…

This study is testing a blood test that looks for tiny pieces of tumor DNA to see if it can detect cancer recurrence earlier than standard scans. It aims to enroll 100 adults, including people with various solid tumors and healthy volunteers. The goal is to gather information tha…

This study aims to understand the course of rare cancers in the urinary system (like bladder, kidney, and prostate cancers) by tracking patients over time. Researchers will collect medical information, blood, urine, and sometimes tumor samples from about 1,100 adults with these c…

This study aims to understand how many opioid pain pills patients actually take after major cancer surgery and how they dispose of leftover medication. Researchers will survey about 700 patients for 30 days after they leave the hospital to track their pain medication use and disp…