Real-World check: do new cancer drugs deliver outside trials?

NCT ID NCT06724159

Recruiting now Knowledge-focused Sponsor: Spanish Oncology Genito-Urinary Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 500 people with genitourinary cancers (like prostate, bladder, or kidney cancer) to see how well recently approved drugs work in everyday Spanish hospitals. Researchers will collect data from patients already taking these medications, without changing their treatment. The goal is to confirm that results from earlier clinical trials hold up in real-world conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: darolutamide, nivolumab, enfortumab vedotin
What this could lead to: If successful, this study could confirm that new cancer drugs work as well in everyday clinics as they did in earlier trials, helping doctors choose the best treatments.
What could go wrong: This is an observational study, not a controlled trial, so results may be less reliable. It only looks at drugs already approved, so it won't test new experimental treatments.

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Conditions

The condition(s) this trial relates to.

malignant urinary system neoplasm renal cell carcinoma transitional cell carcinoma Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GENITOURINARY CANCERS

Contacts and locations

Locations

Althaia Xarxa Assistencial Universitària de Manresa
NOT_YET_RECRUITING

Manresa, Catalonia, 08243, Spain
Centro Oncológico de Galicia
RECRUITING

A Coruña, Galicia, 15009, Spain
Complejo Asistencial Universitario de Salamanca
RECRUITING

Salamanca, Castille and León, 37007, Spain
Complejo Hospitalario Universitario de Albacete
RECRUITING

Albacete, Albacete, 02006, Spain
Complejo Hospitalario Universitario de Ferrol
RECRUITING

Ferrol, Galicia, 15405, Spain
Complejo Hospitalario Zamora
RECRUITING

Zamora, Castille and León, 49022, Spain
Complejo Hospitalario de Palencia
RECRUITING

Palencia, Castille and León, 34004, Spain
Complexo Hospitalario Universitario de Ourense
RECRUITING

Ourense, Galicia, 32005, Spain
Consorcio Hospital General Universitario de València
RECRUITING

Valencia, Valencia, 46014, Spain
Hospital Arnau de Vilanova
RECRUITING

Valencia, Valencia, 46015, Spain
Hospital Central de la Defensa Gómez Ulla
RECRUITING

Madrid, Madrid, 28047, Spain
Hospital Clínic de Barcelona
RECRUITING

Barcelona, Catalonia, 08036, Spain
Hospital Clínico Universitario Lozano Blesa
RECRUITING

Zaragoza, Aragon, 50009, Spain
Hospital Clínico Universitario de Santiago ~ CHUS
RECRUITING

Santiago de Compostela, Galicia, 15706, Spain
Hospital Clínico Universitario de Valencia
RECRUITING

Valencia, Valencia, 46010, Spain
Hospital Clínico Universitario de Valladolid (HCUV)
RECRUITING

Valladolid, Castille and León, 47003, Spain
Hospital Galdakao-Usansolo Ospitalea
RECRUITING

Galdakao, Basque Country, 48960, Spain
Hospital General Mateu Orfila
RECRUITING

Mahón, Balearic Islands, 07703, Spain
Hospital General Universitario Gregorio Marañon
RECRUITING

Madrid, Madrid, 28007, Spain
Hospital General Universitario Morales Meseguer
RECRUITING

Murcia, Murcia, 30008, Spain
Hospital General Universitario de Alicante
RECRUITING

Alicante, Alicante, 03010, Spain
Hospital General Universitario de Ciudad Real
RECRUITING

Ciudad Real, Castille-La Mancha, 13005, Spain
Hospital General de Requena
RECRUITING

Requena, Valencia, 46340, Spain
Hospital General de Segovia
RECRUITING

Segovia, Castille and León, 40002, Spain
Hospital Lluis Alcanyís de Xàtiva
RECRUITING

Xàtiva, Valencia, 46800, Spain
Hospital Marina Baixa
RECRUITING

Villajoyosa, Valencia, 03570, Spain
Hospital Materno Infantil de Gran Canaria
RECRUITING

Las Palmas de Gran Canaria, Canary Islands, 35016, Spain
Hospital Quirón Salud Sagrado Corazón de Sevilla
NOT_YET_RECRUITING

Seville, Andalusia, 41013, Spain
Hospital San Pedro de Alcántara
RECRUITING

Cáceres, Extremadura, 10003, Spain
Hospital Son Espases
RECRUITING

Palma de Mallorca, Balearic Islands, 07120, Spain
Hospital Universitari General de Catalunya
RECRUITING

Sant Cugat Del Vallés, Catalonia, 08195, Spain
Hospital Universitari Parc Taulí, Sabadell
RECRUITING

Sabadell, Catalonia, 08208, Spain
Hospital Universitari Vall d'Hebrón
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitario Basurto
RECRUITING

Bilbao, Basque Country, 48013, Spain
Hospital Universitario Central de Asturias
RECRUITING

Oviedo, Principality of Asturias, 33011, Spain
Hospital Universitario Clínico San Cecilio
RECRUITING

Granada, Andalusia, 18007, Spain
Hospital Universitario Doctor Peset
RECRUITING

Valencia, Valencia, 46017, Spain
Hospital Universitario Fundación Jiménez Díaz
RECRUITING

Madrid, Madrid, 28040, Spain
Hospital Universitario Infanta Leonor
RECRUITING

Vallecas, Madrid, 28031, Spain
Hospital Universitario Infanta Sofía
RECRUITING

San Sebastián, Madrid, 28702, Spain
Hospital Universitario Jerez de la Frontera
RECRUITING

Jerez de la Frontera, Andalusia, 11407, Spain
Hospital Universitario Lucus Augusti
RECRUITING

Lugo, Galicia, 27003, Spain
Hospital Universitario Mancha Centro
RECRUITING

Alcázar de San Juan, Castille-La Mancha, 13600, Spain
Hospital Universitario Miguel Servet
RECRUITING

Zaragoza, Aragon, 50009, Spain
Hospital Universitario Príncipe de Asturias
RECRUITING

Alcalá de Henares, Madrid, 28805, Spain
Hospital Universitario Puerta de Hierro
RECRUITING

Majadahonda, Madrid, 28222, Spain
Hospital Universitario Quironsalud Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, Madrid, 28034, Spain
Hospital Universitario Reina Sofía
RECRUITING

Córdoba, Andalusia, 14004, Spain
Hospital Universitario San Jorge
RECRUITING

Huesca, Aragon, 22004, Spain
Hospital Universitario San Pedro
RECRUITING

Logroño, La Rioja, 26006, Spain
Hospital Universitario Severo Ochoa
RECRUITING

Leganés, Madrid, 28914, Spain
Hospital Universitario Son Llàtzer
RECRUITING

Palma de Mallorca, Balearic Islands, 07198, Spain
Hospital Universitario Torrecárdenas
RECRUITING

Almería, Andalusia, 04009, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, Andalusia, 41009, Spain
Hospital Universitario Virgen a de las Nieves
RECRUITING

Granada, Andalusia, 18014, Spain
Hospital Universitario Virgen de Valme
RECRUITING

Seville, Andalusia, 41014, Spain
Hospital Universitario Virgen de la Arrixaca
RECRUITING

El Palmar, Murcia, 30120, Spain
Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, Andalusia, 29010, Spain
Hospital Universitario Virgen del Rocío
RECRUITING

Seville, Andalusia, 41013, Spain
Hospital Universitario de A Coruña (CHUAC)
RECRUITING

A Coruña, Galicia, 15006, Spain
Hospital Universitario de Badajoz
RECRUITING

Badajoz, Extremadura, 06080, Spain
Hospital Universitario de Burgos
RECRUITING

Burgos, Castille and León, 09006, Spain
Hospital Universitario de Cabueñes
RECRUITING

Gijón, Principality of Asturias, 33394, Spain
Hospital Universitario de Cruces
RECRUITING

Barakaldo, Basque Country, 48903, Spain
Hospital Universitario de Getafe
RECRUITING

Getafe, Madrid, 28905, Spain
Hospital Universitario de Guadalajara
RECRUITING

Guadalajara, Castille-La Mancha, 19002, Spain
Hospital Universitario de Jaén
RECRUITING

Jaén, Andalusia, 23007, Spain
Hospital Universitario de Móstoles
RECRUITING

Móstoles, Madrid, 28935, Spain
Hospital Universitario de Navarra
RECRUITING

Pamplona, Navarre, 31008, Spain
Hospital Universitario de Toledo
RECRUITING

Toledo, Spain
Hospital Universitario de Torrevieja
RECRUITING

Torrevieja, Valencia, 03186, Spain
Hospital Universitario de la Ribera
RECRUITING

Alzira, Valencia, 46600, Spain
Hospital Universitario de Álava - Txagorritxu
RECRUITING

Vitoria-Gasteiz, Basque Country, 01009, Spain
Hospital Universitario del Vinalopó
RECRUITING

Elche, Valencia, 03293, Spain
Hospital Universitario y Politécnico La Fe
RECRUITING

Valencia, Valencia, 46026, Spain
Hospital Virgen de la Luz
RECRUITING

Cuenca, Castille-La Mancha, 16002, Spain
Hospital Virgen de los Lirios
RECRUITING

Alcoy, Valencia, 03804, Spain
Hospital de Sagunto
RECRUITING

Sagunto, Valencia, 46520, Spain
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, Catalonia, 08025, Spain
Hospital del Mar
RECRUITING

Barcelona, Catalonia, 08003, Spain
Hospital Álvaro Cunqueiro
RECRUITING

Vigo, Galicia, 36312, Spain
Instituto Valenciano de Oncología
RECRUITING

Valencia, Valencia, 46009, Spain
OSI Donostialdea - Onkologikoa
RECRUITING

Donostia / San Sebastian, Basque Country, 20014, Spain

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