GENETIC PREDISPOSITION TO DISEASE
Clinical trials for GENETIC PREDISPOSITION TO DISEASE explained in plain language.
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Could a common drug protect the brain from Alzheimer's?
Knowledge-focused OngoingThis early study tests whether sirolimus, an FDA-approved drug, can improve blood flow to the brain in healthy adults with a genetic risk for Alzheimer's disease. Researchers will use MRI scans to measure changes after 4 weeks of daily low-dose sirolimus. The study also explores …
Matched conditions: GENETIC PREDISPOSITION TO DISEASE
Phase: PHASE1 • Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Gene clue could lead to surgical cure for some high blood pressure patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at a specific genetic change found in some people with high blood pressure. Researchers want to see if this change is linked to a condition called primary aldosteronism, which can sometimes be cured with surgery. About 76 men from a larger Swedish health study wh…
Matched conditions: GENETIC PREDISPOSITION TO DISEASE
Phase: NA • Sponsor: Linkoeping University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Genetic prostate cancer screening study aims to catch tumors early
Knowledge-focused OngoingThe IMPACT study is an international effort to screen men aged 40-69 who carry BRCA1, BRCA2, or mismatch repair gene mutations, which raise their risk of prostate cancer. Participants receive annual PSA tests and optional biopsies if levels are high. The goal is to learn how ofte…
Matched conditions: GENETIC PREDISPOSITION TO DISEASE
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Massive study seeks genetic clues to protect black HIV patients from organ damage
Knowledge-focused OngoingThis study follows over 3,000 Black people with HIV in the UK to understand how genes and lifestyle affect their risk for kidney disease, heart disease, diabetes, and obesity. Researchers collect health data and blood/urine samples to find genetic markers that predict these condi…
Matched conditions: GENETIC PREDISPOSITION TO DISEASE
Sponsor: King's College Hospital NHS Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:23 UTC