GASTROINTESTINAL STROMAL TUMORS
Clinical trials for GASTROINTESTINAL STROMAL TUMORS explained in plain language.
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New hope for hard-to-treat GIST: drug combo targets resistant tumors
Disease control Recruiting nowThis study tests a combination of two drugs, rivoceranib and paclitaxel, in people with advanced gastrointestinal stromal tumors (GIST) that have a specific marker (high P-glycoprotein) and have stopped responding to three standard treatments. The goal is to see if this combo can…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated May 17, 2026 03:10 UTC
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New hope for rare stomach cancer: chemo drug targets genetic weakness
Disease control Recruiting nowThis study tests the chemotherapy drug temozolomide in people with advanced gastrointestinal stromal tumors (GIST) that lack a certain enzyme (SDH deficiency). About 29 adults will receive the drug to see if it shrinks tumors and controls the disease. The goal is to offer a new t…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated May 15, 2026 12:07 UTC
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Could a nerve drug boost GIST treatment? new trial launches
Disease control Recruiting nowThis early-phase study tests adding fampridine to standard imatinib (Gleevec) in people with a specific type of gastrointestinal stromal tumor (GIST) that has a KIT gene mutation. The goal is to find the safest dose of the combination and see if it shrinks tumors before surgery. …
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE1 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New hope for GIST patients: oral paclitaxel targets Drug-Resistant tumors
Disease control Recruiting nowThis study tests an oral form of paclitaxel (Liporaxel) in 28 adults with advanced gastrointestinal stromal tumors (GIST) that no longer respond to three standard treatments. The goal is to see if the drug can control tumor growth for at least 16 weeks. Participants must have low…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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DNA-Guided drug switch may improve stomach cancer control
Disease control Recruiting nowThis study tests whether DNA changes in the KIT gene can help doctors choose the right drug for people with advanced gastrointestinal stromal tumor (GIST). About 48 adults whose cancer has worsened on imatinib will receive sunitinib or regorafenib based on their tumor's DNA. The …
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: University of Miami • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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New drug targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis early-stage trial tests a new drug, NN3201, designed to attack cancer cells that have a specific marker called c-Kit. The study includes people with advanced or spreading cancers like gastrointestinal stromal tumors (GIST), small-cell lung cancer, and others. The main goal i…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE1 • Sponsor: Novelty Nobility, Inc. • Aim: Disease control
Last updated May 04, 2026 16:25 UTC
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Drug level check may ease GIST treatment side effects
Symptom relief Recruiting nowThis study looks at whether regularly checking the amount of imatinib in the blood can help reduce side effects and improve quality of life for people with gastrointestinal stromal tumors (GIST). About 28 adults who are starting or recently started imatinib will have their drug l…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Reema A. Patel • Aim: Symptom relief
Last updated May 17, 2026 03:12 UTC
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Can a nurse check on you from home as well as a doctor can?
Knowledge-focused Recruiting nowThis study looks at whether follow-up care for people with rare tumors can be done just as well by a nurse remotely as by a doctor in person. About 88 adults recently diagnosed with a rare tumor will be randomly assigned to either in-person doctor visits or remote nurse check-ins…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated May 04, 2026 16:24 UTC
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Massive cancer registry aims to unlock secrets of the disease
Knowledge-focused Recruiting nowThis study is creating a large database of medical information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. The goal is to help researchers better understand what causes cancer, how it progresses, and how to improve p…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC