GASTROESOPHAGEAL ADENOCARCINOMA
Clinical trials for GASTROESOPHAGEAL ADENOCARCINOMA explained in plain language.
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New hope for advanced stomach cancer: experimental combo targets HER2-positive tumors
Disease control OngoingThis study tests whether a new drug called zanidatamab, combined with chemotherapy and sometimes another drug (tislelizumab), works better than the current standard treatment for advanced HER2-positive stomach and esophageal cancers. About 920 adults whose cancer has spread or ca…
Matched conditions: GASTROESOPHAGEAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New combo aims to keep stomach cancer at bay longer
Disease control OngoingThis phase 2 trial is testing whether adding radiation therapy to the immunotherapy drug nivolumab can help people with advanced gastroesophageal cancer live longer without their disease getting worse. All 80 participants first receive a short course of chemotherapy (FOLFOX) plus…
Matched conditions: GASTROESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Supercharged t cells take on Hard-to-Treat cancers
Disease control TEMPORARILY_NOT_AVAILABLEThis treatment program tests a personalized cell therapy for people with advanced pancreatic or colorectal cancers that have a specific genetic mutation (KRAS G12D). Patients' own immune cells are collected, genetically engineered to recognize and attack the cancer, and then infu…
Matched conditions: GASTROESOPHAGEAL ADENOCARCINOMA
Sponsor: Providence Health & Services • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Gene-Guided chemo aims to boost surgery success in stomach cancer
Disease control TerminatedThis pilot trial tests whether using a patient's genetic profile to determine the dose of irinotecan (a chemotherapy drug) can improve outcomes for people with advanced stomach or esophageal cancer. The study combines chemotherapy before and after surgery, with the goal of increa…
Matched conditions: GASTROESOPHAGEAL ADENOCARCINOMA
Phase: PHASE4 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New hope for advanced cancers: ABBV-400 enters human trials
Disease control OngoingThis early-phase study tests an experimental drug called ABBV-400, alone or with another drug (bevacizumab), in about 520 adults with advanced solid tumors including lung, stomach, and colorectal cancers. The goal is to find the safest and most effective dose and see if it can sh…
Matched conditions: GASTROESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Cancer biobank study aims to unlock secrets of immunotherapy resistance
Knowledge-focused TerminatedThis observational study collects blood and tumor tissue samples from people with gastroesophageal cancer to study genetic changes that may cause resistance to immunotherapy. It does not involve any treatment or experimental drugs. The goal is to identify new targets for future i…
Matched conditions: GASTROESOPHAGEAL ADENOCARCINOMA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC