FRACTURES, OPEN
Clinical trials for FRACTURES, OPEN explained in plain language.
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Can a simple antibiotic shot stop open fracture infections?
Disease control OngoingThis phase 3 trial tests whether adding a local injection of the antibiotic tobramycin to standard IV antibiotics can lower infection rates after open fracture surgery. Open fractures have a high risk of infection because the wound may not get enough blood flow for IV antibiotics…
Matched conditions: FRACTURES, OPEN
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Can shorter antibiotic courses prevent infections in Kids' broken bones?
Disease control ENROLLING_BY_INVITATIONThis study looks at 800 children with mild open fractures to see how much antibiotic is needed to prevent infections. Some kids get one dose, some get 24 hours, and some get 24 hours plus five days of pills. The goal is to find the best balance between preventing infection and av…
Matched conditions: FRACTURES, OPEN
Phase: PHASE4 • Sponsor: St. Louis University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC