ESCC
Clinical trials for ESCC explained in plain language.
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New drug duo aims to wipe out esophageal tumors before surgery
Disease control Recruiting nowThis study tests whether giving two drugs (anlotinib and bemocizumab) before surgery can improve outcomes for people with resectable esophageal squamous cell carcinoma. About 25 adults with stage II-IIIB disease will receive the combination, then undergo surgery. The main goal is…
Matched conditions: ESCC
Phase: NA • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New 'Smart Bomb' drug targets Hard-to-Treat cancers in first human trial
Disease control Recruiting nowThis early-stage study is testing a new drug called ALX2004 in people with advanced lung, head and neck, esophageal, or colorectal cancers that have not responded to standard treatments. ALX2004 is an antibody-drug conjugate designed to deliver a cancer-killing payload directly t…
Matched conditions: ESCC
Phase: PHASE1 • Sponsor: ALX Oncology Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New drug NRM-823 takes on Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase trial is testing a new drug called NRM-823, alone or with immunotherapy, in people with advanced solid tumors like lung, ovarian, or breast cancer that haven't responded to standard treatments. The study aims to see if the drug is safe and tolerable. About 150 pa…
Matched conditions: ESCC
Phase: PHASE1 • Sponsor: Normunity AccelCo, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New combo therapy before surgery shows promise for tough esophageal cancer
Disease control Recruiting nowThis study tests a new approach for people with locally advanced esophageal cancer. Participants first receive a combination of immunotherapy and chemotherapy, then chemoradiation, followed by surgery. The goal is to see if this sequence can shrink tumors more effectively and imp…
Matched conditions: ESCC
Phase: PHASE2 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New hope for advanced cancers? JAB-8263 enters human testing
Disease control Recruiting nowThis study tests a new drug called JAB-8263 in adults with advanced solid tumors or blood cancers that have stopped responding to standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. About 152 people will take part in this early-phase trial.
Matched conditions: ESCC
Phase: PHASE1, PHASE2 • Sponsor: Jacobio Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New blood test aims to detect deadly esophageal cancer before It's too late
Diagnosis Recruiting nowThe SYNERGY study is developing a blood test that looks for tiny genetic molecules called microRNAs to detect esophageal squamous cell carcinoma (ESCC) at an early, more treatable stage. Researchers will collect blood samples from 600 adults with and without ESCC to build and val…
Matched conditions: ESCC
Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC