New blood test aims to detect deadly esophageal cancer before It's too late
NCT ID NCT07266363
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
The SYNERGY study is developing a blood test that looks for tiny genetic molecules called microRNAs to detect esophageal squamous cell carcinoma (ESCC) at an early, more treatable stage. Researchers will collect blood samples from 600 adults with and without ESCC to build and validate a diagnostic model. If successful, this non-invasive test could replace or complement current invasive screening methods like endoscopy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Blood-based microRNA assay (SYNERGY assay)
What this could lead to
If successful, this could lead to a simple blood test that catches esophageal cancer early, when it is more treatable, potentially saving lives.
What could go wrong
This is an early-stage study with 600 participants, so the test may not prove accurate enough for widespread use. It is not yet ready for clinical practice.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Medical Center
RECRUITINGMonrovia, California, 91016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••