ER-POSITIVE, HER2-NEGATIVE BREAST CANCER
Clinical trials for ER-POSITIVE, HER2-NEGATIVE BREAST CANCER explained in plain language.
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BREAST CANCER BREAKTHROUGH? new study lets patients choose chemo-free treatment
Disease control Recruiting nowThis study is for people with a common type of breast cancer (ER-positive, HER2-negative) that has a moderate to high risk of coming back based on tumor size and lymph node involvement, but a low genetic risk score. Instead of chemotherapy after surgery, participants can choose t…
Matched conditions: ER-POSITIVE, HER2-NEGATIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 16, 2026 20:35 UTC
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New hope for tough breast cancer: experimental drug combo targets resistant tumors
Disease control Recruiting nowThis study tests a new experimental drug (GDC-0587) alone or with another drug (giredestrant) in people with advanced ER-positive, HER2-negative breast cancer whose cancer got worse after CDK4/6 inhibitor therapy. The main goals are to check safety and find the right dose. About …
Matched conditions: ER-POSITIVE, HER2-NEGATIVE BREAST CANCER
Phase: PHASE1 • Sponsor: Genentech, Inc. • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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New hope: pill aims to wipe out hidden breast cancer cells
Disease control Recruiting nowThis study tests whether the chemotherapy drug capecitabine can clear tiny traces of cancer DNA found in the blood of people with ER+/HER2- breast cancer after standard treatment. About 15 adults whose cancer has been surgically removed but still show signs of residual disease wi…
Matched conditions: ER-POSITIVE, HER2-NEGATIVE BREAST CANCER
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC