EGFR
Clinical trials for EGFR explained in plain language.
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New pill aims to keep early lung cancer from coming back after surgery
Disease control OngoingThis study tests whether adding the drug zipalertinib to standard chemotherapy after lung cancer surgery helps prevent the cancer from returning. It is for people with early-stage (IB-IIIA) non-small cell lung cancer that has specific uncommon EGFR mutations. About 360 participan…
Matched conditions: EGFR
Phase: PHASE3 • Sponsor: Taiho Oncology, Inc. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for hard-to-treat cancers: experimental drug enters human testing
Disease control OngoingThis early-stage study tests a new drug called TT125-802 in about 50 adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check the drug's safety and find the best dose. Researchers will also watch for signs that the drug sh…
Matched conditions: EGFR
Phase: PHASE1 • Sponsor: TOLREMO therapeutics AG • Aim: Disease control
Last updated May 06, 2026 16:02 UTC
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Lung cancer clue: DNA repair flaw may guide future treatments
Knowledge-focused OngoingThis study examines 100 people with a certain type of advanced lung cancer (EGFR-mutated NSCLC) to see how often they have a DNA repair problem called HRD. Researchers will look at tumor samples and medical records to find links between HRD and how the cancer behaves. The goal is…
Matched conditions: EGFR
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 17, 2026 07:34 UTC
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Smartphone app and fitbit join forces to monitor lung cancer treatment side effects
Knowledge-focused OngoingThis study involves 30 adults with lung cancer who are taking oral targeted therapy (TKIs). Participants use a smartphone app, a Fitbit, and a smart pill cap for up to 24 weeks to track symptoms and medication use. The goal is to see if this remote system is practical and to guid…
Matched conditions: EGFR
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated May 05, 2026 11:53 UTC