EARLY BREAST CANCER

This study tests whether adding ribociclib to standard hormone therapy can help prevent breast cancer from returning in people with HR+ HER2- early breast cancer. About 1,400 adults with stage II or III disease will receive the combination for up to 3 years. Researchers will trac…

This study tests whether an MRI scan can identify patients with triple-negative breast cancer who respond well to the first part of chemotherapy, allowing them to skip the second, more toxic part. About 54 participants will receive an initial chemo-immunotherapy combination, then…

This study looks at whether eating a Mediterranean diet (rich in vegetables, fruits, nuts, and fish) can improve gut health, quality of life, and treatment outcomes for 105 women with early breast cancer undergoing chemotherapy. Participants will either follow the Mediterranean d…

This study tests whether a smartphone app combined with nurse phone calls can help cancer patients manage chemotherapy side effects and improve their quality of life. About 414 adults with early or advanced stomach, lung, breast, or colon cancer will participate. The goal is to s…

This study tests a new handheld robotic tool, HandX, to help surgeons perform nipple-sparing mastectomy through a single small incision. The goal is to reduce scarring and improve comfort after surgery. About 15 women already scheduled for mastectomy will take part, and researche…

This study looks at how well women with early-stage, hormone-positive breast cancer take their prescribed medications (aromatase inhibitors with or without abemaciclib). About 319 participants will be followed for 6 months to see if those on the combination therapy have lower adh…

This study aims to create a detailed map of the tiny structures inside breast cancer cells, such as fat droplets and other organelles, across different cancer subtypes. Researchers will collect tissue samples from 1,050 people with early or metastatic breast cancer and analyze th…