DYSTHYMIA
Clinical trials for DYSTHYMIA explained in plain language.
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Can a 10-Week program shield kids from depression?
Prevention CompletedThis study tested a 10-week program called the Protecting Families Program (PFP) for depressed parents and their pre-teen children. The goal was to see if the program could prevent depression in the children. 42 families took part, with parents in treatment for depression. The pr…
Matched conditions: DYSTHYMIA
Phase: PHASE1 • Sponsor: Children's Hospital of Philadelphia • Aim: Prevention
Last updated Jun 27, 2026 08:09 UTC
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Could a Parkinson's drug help treat a key symptom of depression?
Symptom relief CompletedThis study tested whether pramipexole, a drug used for Parkinson's disease, can help people with depression who still have trouble feeling pleasure or motivation despite taking standard antidepressants. 85 adults with depression and significant anhedonia took either pramipexole o…
Matched conditions: DYSTHYMIA
Phase: PHASE3 • Sponsor: Region Skane • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Could a Parkinson's drug help restore pleasure in depression?
Symptom relief CompletedThis study looked at whether adding pramipexole (a drug used for Parkinson's) for 6 months can safely reduce anhedonia — the loss of pleasure or interest — in people with depression. 55 adults who had already been in a shorter trial took pramipexole alongside their usual treatmen…
Matched conditions: DYSTHYMIA
Phase: PHASE3 • Sponsor: Region Skane • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Parkinson's drug shows promise for Depression's pleasure loss
Symptom relief CompletedThis pilot study tested whether pramipexole, a drug used for Parkinson's disease, could help people with depression who struggle with anhedonia—the inability to feel pleasure or motivation. Thirteen adults with depression and significant anhedonia took pramipexole alongside their…
Matched conditions: DYSTHYMIA
Phase: PHASE2 • Sponsor: Region Skane • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC